All Phenotypes Npc1<tm1b(EUCOMM)Hmgu> MGI Mouse

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Npc1^{tm1b(EUCOMM)Hmgu}
targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
MGI:5636924

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Npc1^{tm1b(EUCOMM)Hmgu}/Npc1^{tm1b(EUCOMM)Hmgu}	C57BL/6N-Npc1^{tm1b(EUCOMM)Hmgu}/H	MGI:5757427
ht2	Npc1^{tm1b(EUCOMM)Hmgu}/Npc1⁺	C57BL/6N-Npc1^{tm1b(EUCOMM)Hmgu}/H	MGI:5757426

Allelic Composition	Npc1^{tm1b(EUCOMM)Hmgu}/Npc1^{tm1b(EUCOMM)Hmgu}
Genetic Background	C57BL/6N-Npc1^{tm1b(EUCOMM)Hmgu}/H
Cell Lines	HEPD0534_4_G05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Npc1^{tm1b(EUCOMM)Hmgu} mutation (0 available); any Npc1 mutation (74 available)

Data Sources

IMPC Data for Npc1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HAR

Allelic Composition	Npc1^{tm1b(EUCOMM)Hmgu}/Npc1⁺
Genetic Background	C57BL/6N-Npc1^{tm1b(EUCOMM)Hmgu}/H
Cell Lines	HEPD0534_4_G05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Npc1^{tm1b(EUCOMM)Hmgu} mutation (0 available); any Npc1 mutation (74 available)

Data Sources

IMPC Data for Npc1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

decreased exploration in new environment ( J:211773 )

IMPC - HAR

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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