Phenotypes associated with this allele

• Allele Symbol: Gfi1b^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5636937
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gfi1b^tm1b(EUCOMM)Hmgu/Gfi1b^tm1b(EUCOMM)Hmgu	C57BL/6N-Gfi1b^tm1b(EUCOMM)Hmgu/H	MGI:5757165
ht2	Gfi1b^tm1b(EUCOMM)Hmgu/Gfi1b^+	C57BL/6N-Gfi1b^tm1b(EUCOMM)Hmgu/H	MGI:6262517

Genotype
MGI:5757165

hm1

• Allelic Composition: Gfi1b^{tm1b(EUCOMM)Hmgu}/Gfi1b^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Gfi1b^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0515_4_E11

Data Sources

IMPC Data for Gfi1b

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

prenatal lethality ( J:211773 )

IMPC - HAR

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:6262517

ht2

• Allelic Composition: Gfi1b^{tm1b(EUCOMM)Hmgu}/Gfi1b⁺
• Genetic Background: C57BL/6N-Gfi1b^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0515_4_E11

Data Sources

IMPC Data for Gfi1b

adipose tissue

increased total body fat amount ( J:211773 )

♂

IMPC - HAR

hematopoietic system

decreased neutrophil cell number ( J:211773 )

♂

IMPC - HAR

increased lymphocyte cell number ( J:211773 )

♂

IMPC - HAR

homeostasis/metabolism

increased circulating bilirubin level ( J:211773 )

IMPC - HAR

increased circulating serum albumin level ( J:211773 )

♂

IMPC - HAR

immune system

decreased neutrophil cell number ( J:211773 )

♂

IMPC - HAR

increased lymphocyte cell number ( J:211773 )

♂

IMPC - HAR