Phenotypes associated with this allele

• Allele Symbol: Rexo2^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5636999
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rexo2^tm1b(EUCOMM)Wtsi/Rexo2^tm1b(EUCOMM)Wtsi	C57BL/6N-Rexo2^tm1b(EUCOMM)Wtsi/H	MGI:5757617
ht2	Rexo2^tm1b(EUCOMM)Wtsi/Rexo2^+	C57BL/6N-Rexo2^tm1b(EUCOMM)Wtsi/H	MGI:5757616

Genotype
MGI:5757617

hm1

• Allelic Composition: Rexo2^{tm1b(EUCOMM)Wtsi}/Rexo2^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Rexo2^{tm1b(EUCOMM)Wtsi}/H
• Cell Lines: EPD0338_1_G10

Data Sources

IMPC Data for Rexo2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:5757616

ht2

• Allelic Composition: Rexo2^{tm1b(EUCOMM)Wtsi}/Rexo2⁺
• Genetic Background: C57BL/6N-Rexo2^{tm1b(EUCOMM)Wtsi}/H
• Cell Lines: EPD0338_1_G10

Data Sources

IMPC Data for Rexo2

hematopoietic system

decreased neutrophil cell number ( J:211773 )

♂

IMPC - HAR

increased lymphocyte cell number ( J:211773 )

♂

IMPC - HAR

homeostasis/metabolism

decreased fasting circulating glucose level ( J:211773 )

♂

IMPC - HAR

increased circulating cholesterol level ( J:211773 )

♂

IMPC - HAR

increased circulating HDL cholesterol level ( J:211773 )

♂

IMPC - HAR

increased circulating serum albumin level ( J:211773 )

♂

IMPC - HAR

immune system

decreased neutrophil cell number ( J:211773 )

♂

IMPC - HAR

increased lymphocyte cell number ( J:211773 )

♂

IMPC - HAR