Phenotypes associated with this allele

• Allele Symbol: Gabarapl2^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5637004
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gabarapl2^tm1b(EUCOMM)Hmgu/Gabarapl2^tm1b(EUCOMM)Hmgu	C57BL/6N-Gabarapl2^tm1b(EUCOMM)Hmgu/H	MGI:5757150
ht2	Gabarapl2^tm1b(EUCOMM)Hmgu/Gabarapl2^+	C57BL/6N-Gabarapl2^tm1b(EUCOMM)Hmgu/H	MGI:5757149

Genotype
MGI:5757150

hm1

• Allelic Composition: Gabarapl2^{tm1b(EUCOMM)Hmgu}/Gabarapl2^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Gabarapl2^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0559_2_F09

Data Sources

IMPC Data for Gabarapl2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:5757149

ht2

• Allelic Composition: Gabarapl2^{tm1b(EUCOMM)Hmgu}/Gabarapl2⁺
• Genetic Background: C57BL/6N-Gabarapl2^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0559_2_F09

Data Sources

IMPC Data for Gabarapl2

cardiovascular system

increased heart weight ( J:211773 )

♂

IMPC - HAR

growth/size/body

increased heart weight ( J:211773 )

♂

IMPC - HAR

hematopoietic system

decreased hemoglobin content ( J:211773 )

♂

IMPC - HAR

increased neutrophil cell number ( J:211773 )

♂

IMPC - HAR

decreased lymphocyte cell number ( J:211773 )

IMPC - HAR

increased monocyte cell number ( J:211773 )

♂

IMPC - HAR

homeostasis/metabolism

decreased circulating serum albumin level ( J:211773 )

♂

IMPC - HAR

immune system

increased neutrophil cell number ( J:211773 )

♂

IMPC - HAR

decreased lymphocyte cell number ( J:211773 )

IMPC - HAR

increased monocyte cell number ( J:211773 )

♂

IMPC - HAR