Phenotypes associated with this allele

• Allele Symbol: Pde4dip^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5637006
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pde4dip^tm1b(KOMP)Wtsi/Pde4dip^tm1b(KOMP)Wtsi	C57BL/6N-Pde4dip^tm1b(KOMP)Wtsi/Bay	MGI:6263120
ht2	Pde4dip^tm1b(KOMP)Wtsi/Pde4dip^+	C57BL/6N-Pde4dip^tm1b(KOMP)Wtsi/Bay	MGI:6263119

Genotype
MGI:6263120

hm1

• Allelic Composition: Pde4dip^{tm1b(KOMP)Wtsi}/Pde4dip^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Pde4dip^{tm1b(KOMP)Wtsi}/Bay
• Cell Lines: EPD0727_5_G09

Data Sources

IMPC Data for Pde4dip

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - BCM

Genotype
MGI:6263119

ht2

• Allelic Composition: Pde4dip^{tm1b(KOMP)Wtsi}/Pde4dip⁺
• Genetic Background: C57BL/6N-Pde4dip^{tm1b(KOMP)Wtsi}/Bay
• Cell Lines: EPD0727_5_G09

Data Sources

IMPC Data for Pde4dip

hematopoietic system

increased hemoglobin content ( J:211773 )

♂

IMPC - BCM

skeleton

increased bone mineral content ( J:211773 )

♂

IMPC - BCM

vision/eye

increased cornea thickness ( J:211773 )

♀

IMPC - BCM

abnormal eye anterior chamber depth ( J:211773 )

♀

IMPC - BCM

abnormal retina outer nuclear layer morphology ( J:211773 )

IMPC - BCM

decreased total retina thickness ( J:211773 )

IMPC - BCM