Phenotypes associated with this allele

• Allele Symbol: Rwdd1^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5637013
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rwdd1^tm1b(KOMP)Wtsi/Rwdd1^tm1b(KOMP)Wtsi	C57BL/6N-Rwdd1^tm1b(KOMP)Wtsi/Wtsi	MGI:5797786

Genotype
MGI:5797786

hm1

• Allelic Composition: Rwdd1^{tm1b(KOMP)Wtsi}/Rwdd1^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Rwdd1^{tm1b(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0165_5_B04

Data Sources

IMPC Data for Rwdd1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased total body fat amount ( J:211773 )

♀

IMPC - WTSI

hematopoietic system

thrombocytopenia ( J:211773 )

♂

IMPC - WTSI

decreased Ly6C-positive mature NK cell number ( J:211773 )

IMPC - WTSI

increased CD4-positive, alpha-beta T cell number ( J:211773 )

IMPC - WTSI

decreased CD8-positive, alpha-beta T cell number ( J:211773 )

IMPC - WTSI

increased memory-marker gamma-delta T cell number ( J:211773 )

IMPC - WTSI

decreased regulatory T cell number ( J:211773 )

♂

IMPC - WTSI

homeostasis/metabolism

increased circulating bilirubin level ( J:211773 )

♂

IMPC - WTSI

increased circulating triglyceride level ( J:211773 )

♂

IMPC - WTSI

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - WTSI

immune system

decreased Ly6C-positive mature NK cell number ( J:211773 )

IMPC - WTSI

increased CD4-positive, alpha-beta T cell number ( J:211773 )

IMPC - WTSI

decreased CD8-positive, alpha-beta T cell number ( J:211773 )

IMPC - WTSI

increased memory-marker gamma-delta T cell number ( J:211773 )

IMPC - WTSI

decreased regulatory T cell number ( J:211773 )

♂

IMPC - WTSI

skeleton

abnormal bone structure ( J:211773 )

♀

IMPC - WTSI

decreased bone mineral content ( J:211773 )

♀

IMPC - WTSI

vision/eye

abnormal retina morphology ( J:211773 )

♀

IMPC - WTSI