Phenotypes associated with this allele

• Allele Symbol: Leprotl1^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5637030
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Leprotl1^tm1b(EUCOMM)Hmgu/Leprotl1^tm1b(EUCOMM)Hmgu	C57BL/6N-Leprotl1^tm1b(EUCOMM)Hmgu/H	MGI:5757309

Genotype
MGI:5757309

hm1

• Allelic Composition: Leprotl1^{tm1b(EUCOMM)Hmgu}/Leprotl1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Leprotl1^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0576_6_H12

Data Sources

IMPC Data for Leprotl1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal behavior ( J:211773 )

♂

IMPC - HAR

decreased anxiety-related response ( J:211773 )

♂

IMPC - HAR

decreased thigmotaxis ( J:211773 )

IMPC - HAR

limb grasping ( J:211773 )

IMPC - HAR

decreased locomotor activity ( J:211773 )

IMPC - HAR

cardiovascular system

abnormal heart left ventricle morphology ( J:211773 )

♀

IMPC - HAR

thick ventricular wall ( J:211773 )

♀

IMPC - HAR

increased cardiac muscle contractility ( J:211773 )

♀

IMPC - HAR

increased heart rate ( J:211773 )

♀

IMPC - HAR

homeostasis/metabolism

increased circulating phosphate level ( J:211773 )

♂

IMPC - HAR

increased circulating alanine transaminase level ( J:211773 )

♂

IMPC - HAR

increased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - HAR

muscle

increased cardiac muscle contractility ( J:211773 )

♀

IMPC - HAR