Phenotypes associated with this allele

• Allele Symbol: Dnajc8^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5637033
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dnajc8^tm1b(KOMP)Wtsi/Dnajc8^tm1b(KOMP)Wtsi	C57BL/6N-Dnajc8^tm1b(KOMP)Wtsi/Wtsi	MGI:5767637
ht2	Dnajc8^tm1b(KOMP)Wtsi/Dnajc8^+	C57BL/6N-Dnajc8^tm1b(KOMP)Wtsi/Wtsi	MGI:5797484

Genotype
MGI:5767637

hm1

• Allelic Composition: Dnajc8^{tm1b(KOMP)Wtsi}/Dnajc8^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Dnajc8^{tm1b(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0815_5_A10

Data Sources

IMPC Data for Dnajc8

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal placenta morphology ( J:261316 )

• branching morphology defect at E9.5

abnormal trophoblast layer morphology ( J:261316 )

• small or absent trophoblast compartment at E9.5

abnormal visceral yolk sac morphology ( J:261316 )

• yolk sac abnormalities

mortality/aging

prenatal lethality prior to heart atrial septation ( J:211773 )

IMPC - WTSI

preweaning lethality, complete penetrance ( J:211773 )

IMPC - WTSI

lethality throughout fetal growth and development, complete penetrance ( J:261316 )

• complete lethality at E14.5

Genotype
MGI:5797484

ht2

• Allelic Composition: Dnajc8^{tm1b(KOMP)Wtsi}/Dnajc8⁺
• Genetic Background: C57BL/6N-Dnajc8^{tm1b(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0815_5_A10

Data Sources

IMPC Data for Dnajc8

hematopoietic system

increased mean corpuscular hemoglobin ( J:211773 )

IMPC - WTSI