Phenotypes associated with this allele

• Allele Symbol: Coq2^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5637057
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Coq2^tm1b(EUCOMM)Hmgu/Coq2^tm1b(EUCOMM)Hmgu	C57BL/6N-Coq2^tm1b(EUCOMM)Hmgu/H	MGI:5756905
ht2	Coq2^tm1b(EUCOMM)Hmgu/Coq2^+	C57BL/6N-Coq2^tm1b(EUCOMM)Hmgu/H	MGI:5756904

Genotype
MGI:5756905

hm1

• Allelic Composition: Coq2^{tm1b(EUCOMM)Hmgu}/Coq2^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Coq2^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0678_3_F02

Data Sources

IMPC Data for Coq2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - HAR

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:5756904

ht2

• Allelic Composition: Coq2^{tm1b(EUCOMM)Hmgu}/Coq2⁺
• Genetic Background: C57BL/6N-Coq2^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0678_3_F02

Data Sources

IMPC Data for Coq2

adipose tissue

increased total body fat amount ( J:211773 )

IMPC - HAR

cardiovascular system

decreased heart weight ( J:211773 )

IMPC - HAR

growth/size/body

decreased lean body mass ( J:211773 )

♂

IMPC - HAR

skeleton

decreased bone mineral content ( J:211773 )

IMPC - HAR