Phenotypes associated with this allele

• Allele Symbol: Chic2^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5637077
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Chic2^tm1b(EUCOMM)Wtsi/Chic2^tm1b(EUCOMM)Wtsi	C57BL/6N-Chic2^tm1b(EUCOMM)Wtsi/H	MGI:5756871
ht2	Chic2^tm1b(EUCOMM)Wtsi/Chic2^+	C57BL/6N-Chic2^tm1b(EUCOMM)Wtsi/H	MGI:5756870

Genotype
MGI:5756871

hm1

• Allelic Composition: Chic2^{tm1b(EUCOMM)Wtsi}/Chic2^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Chic2^{tm1b(EUCOMM)Wtsi}/H
• Cell Lines: EPD0701_4_B08

Data Sources

IMPC Data for Chic2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:5756870

ht2

• Allelic Composition: Chic2^{tm1b(EUCOMM)Wtsi}/Chic2⁺
• Genetic Background: C57BL/6N-Chic2^{tm1b(EUCOMM)Wtsi}/H
• Cell Lines: EPD0701_4_B08

Data Sources

IMPC Data for Chic2

cardiovascular system

enlarged heart ( J:211773 )

♀

IMPC - HAR

endocrine/exocrine glands

enlarged ovary ( J:211773 )

♀

IMPC - HAR

growth/size/body

enlarged heart ( J:211773 )

♀

IMPC - HAR

enlarged ovary ( J:211773 )

♀

IMPC - HAR

enlarged spleen ( J:211773 )

♀

IMPC - HAR

hematopoietic system

enlarged spleen ( J:211773 )

♀

IMPC - HAR

homeostasis/metabolism

increased circulating alanine transaminase level ( J:211773 )

IMPC - HAR

increased circulating amylase level ( J:211773 )

♀

IMPC - HAR

immune system

enlarged spleen ( J:211773 )

♀

IMPC - HAR

integument

abnormal coat/hair pigmentation ( J:211773 )

♀

IMPC - HAR

pigmentation

abnormal coat/hair pigmentation ( J:211773 )

♀

IMPC - HAR

reproductive system

enlarged ovary ( J:211773 )

♀

IMPC - HAR

vision/eye

iris synechia ( J:211773 )

♂

IMPC - HAR