All Phenotypes Depdc5<tm1b(EUCOMM)Hmgu> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Depdc5^{tm1b(EUCOMM)Hmgu}
targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
MGI:5637113

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Depdc5^{tm1b(EUCOMM)Hmgu}/Depdc5^{tm1b(EUCOMM)Hmgu}	C57BL/6N-Depdc5^{tm1b(EUCOMM)Hmgu}/H	MGI:5756983
ht2	Depdc5^{tm1b(EUCOMM)Hmgu}/Depdc5⁺	C57BL/6N-Depdc5^{tm1b(EUCOMM)Hmgu}/H	MGI:5756982

Allelic Composition	Depdc5^{tm1b(EUCOMM)Hmgu}/Depdc5^{tm1b(EUCOMM)Hmgu}
Genetic Background	C57BL/6N-Depdc5^{tm1b(EUCOMM)Hmgu}/H
Cell Lines	HEPD0734_3_G10

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Depdc5^{tm1b(EUCOMM)Hmgu} mutation (1 available); any Depdc5 mutation (120 available)

Data Sources

IMPC Data for Depdc5

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Allelic Composition	Depdc5^{tm1b(EUCOMM)Hmgu}/Depdc5⁺
Genetic Background	C57BL/6N-Depdc5^{tm1b(EUCOMM)Hmgu}/H
Cell Lines	HEPD0734_3_G10

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Depdc5^{tm1b(EUCOMM)Hmgu} mutation (1 available); any Depdc5 mutation (120 available)

Data Sources

IMPC Data for Depdc5

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

adipose tissue

increased total body fat amount ( J:211773 )

IMPC - HAR

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - HAR

impaired glucose tolerance ( J:211773 )

IMPC - HAR

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