Phenotypes associated with this allele

• Allele Symbol: Pgap2^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5637131
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pgap2^tm1b(EUCOMM)Wtsi/Pgap2^tm1b(EUCOMM)Wtsi	C57BL/6N-Pgap2^tm1b(EUCOMM)Wtsi/Wtsi	MGI:5767756

Genotype
MGI:5767756

hm1

• Allelic Composition: Pgap2^{tm1b(EUCOMM)Wtsi}/Pgap2^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Pgap2^{tm1b(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0543_5_G04

Data Sources

IMPC Data for Pgap2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal placenta morphology ( J:261316 )

• branching morphology defect

• fibrotic/acellular lesions

abnormal trophoblast layer morphology ( J:261316 )

• small or absent trophoblast compartment

• biased differentiation (diploid/polyploid trophoblast)

abnormal visceral yolk sac morphology ( J:261316 )

• yolk sac abnormalities

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - WTSI

embryonic lethality during organogenesis, complete penetrance ( J:261316 )

• lethality at E9.5-E10.5