Phenotypes associated with this allele

• Allele Symbol: Flnb^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5637156
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Flnb^tm1b(KOMP)Wtsi/Flnb^tm1b(KOMP)Wtsi	C57BL/6N-Flnb^tm1b(KOMP)Wtsi/H	MGI:5757124
ht2	Flnb^tm1b(KOMP)Wtsi/Flnb^+	C57BL/6N-Flnb^tm1b(KOMP)Wtsi/H	MGI:5757123

Genotype
MGI:5757124

hm1

• Allelic Composition: Flnb^{tm1b(KOMP)Wtsi}/Flnb^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Flnb^{tm1b(KOMP)Wtsi}/H
• Cell Lines: EPD0585_1_F09

Data Sources

IMPC Data for Flnb

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:5757123

ht2

• Allelic Composition: Flnb^{tm1b(KOMP)Wtsi}/Flnb⁺
• Genetic Background: C57BL/6N-Flnb^{tm1b(KOMP)Wtsi}/H
• Cell Lines: EPD0585_1_F09

Data Sources

IMPC Data for Flnb

adipose tissue

increased total body fat amount ( J:211773 )

♂

IMPC - HAR

growth/size/body

decreased lean body mass ( J:211773 )

♂

IMPC - HAR

hematopoietic system

decreased red blood cell distribution width ( J:211773 )

♂

IMPC - HAR

decreased neutrophil cell number ( J:211773 )

♂

IMPC - HAR

homeostasis/metabolism

increased circulating serum albumin level ( J:211773 )

♂

IMPC - HAR

immune system

decreased neutrophil cell number ( J:211773 )

♂

IMPC - HAR

skeleton

decreased bone mineral content ( J:211773 )

♂

IMPC - HAR

decreased bone mineral density ( J:211773 )

♂

IMPC - HAR