Phenotypes associated with this allele

• Allele Symbol: Pigl^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5637168
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pigl^tm1b(KOMP)Wtsi/Pigl^tm1b(KOMP)Wtsi	C57BL/6N-Pigl^tm1b(KOMP)Wtsi/Wtsi	MGI:5757516
ht2	Pigl^tm1b(KOMP)Wtsi/Pigl^+	C57BL/6N-Pigl^tm1b(KOMP)Wtsi/Wtsi	MGI:6394359

Genotype
MGI:5757516

hm1

• Allelic Composition: Pigl^{tm1b(KOMP)Wtsi}/Pigl^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Pigl^{tm1b(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0612_4_G02

Data Sources

IMPC Data for Pigl

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal placenta morphology ( J:261316 )

• branching morphology defect

abnormal trophoblast layer morphology ( J:261316 )

• biased differentiation (diploid/polyploid trophoblast)

abnormal visceral yolk sac morphology ( J:261316 )

• yolk sac abnormalities

mortality/aging

prenatal lethality prior to heart atrial septation ( J:211773 )

IMPC - WTSI

preweaning lethality, complete penetrance ( J:211773 )

IMPC - WTSI

embryonic lethality during organogenesis, complete penetrance ( J:261316 )

• lethality at E9.5-E10.5

Genotype
MGI:6394359

ht2

• Allelic Composition: Pigl^{tm1b(KOMP)Wtsi}/Pigl⁺
• Genetic Background: C57BL/6N-Pigl^{tm1b(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0612_4_G02

Data Sources

IMPC Data for Pigl

integument

abnormal vibrissa morphology ( J:211773 )

♂

IMPC - WTSI