Phenotypes associated with this allele

• Allele Symbol: F2^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5637201
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	F2^tm1b(EUCOMM)Hmgu/F2^tm1b(EUCOMM)Hmgu	C57BL/6N-F2^tm1b(EUCOMM)Hmgu/H	MGI:5757070
ht2	F2^tm1b(EUCOMM)Hmgu/F2^+	C57BL/6N-F2^tm1b(EUCOMM)Hmgu/H	MGI:5797523

Genotype
MGI:5757070

hm1

• Allelic Composition: F2^{tm1b(EUCOMM)Hmgu}/F2^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-F2^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0720_4_G11

Data Sources

IMPC Data for F2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:5797523

ht2

• Allelic Composition: F2^{tm1b(EUCOMM)Hmgu}/F2⁺
• Genetic Background: C57BL/6N-F2^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0720_4_G11

Data Sources

IMPC Data for F2

adipose tissue

increased total body fat amount ( J:211773 )

♂

IMPC - HAR

behavior/neurological

decreased exploration in new environment ( J:211773 )

♂

IMPC - HAR

tremors ( J:211773 )

♂

IMPC - HAR

growth/size/body

decreased lean body mass ( J:211773 )

♂

IMPC - HAR

hematopoietic system

decreased mean corpuscular volume ( J:211773 )

IMPC - HAR

homeostasis/metabolism

increased circulating fructosamine level ( J:211773 )

♀

IMPC - HAR

increased circulating serum albumin level ( J:211773 )

♀

IMPC - HAR

skeleton

decreased bone mineral content ( J:211773 )

♂

IMPC - HAR