Phenotypes associated with this allele

• Allele Symbol: Ngfr^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5637211
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ngfr^tm1b(EUCOMM)Wtsi/Ngfr^tm1b(EUCOMM)Wtsi	C57BL/6N-Ngfr^tm1b(EUCOMM)Wtsi/H	MGI:5757418
ht2	Ngfr^tm1b(EUCOMM)Wtsi/Ngfr^+	C57BL/6N-Ngfr^tm1b(EUCOMM)Wtsi/H	MGI:6480525

Genotype
MGI:5757418

hm1

• Allelic Composition: Ngfr^{tm1b(EUCOMM)Wtsi}/Ngfr^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Ngfr^{tm1b(EUCOMM)Wtsi}/H
• Cell Lines: EPD0059_4_D03

Data Sources

IMPC Data for Ngfr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal behavior ( J:211773 )

♂

IMPC - HAR

decreased thigmotaxis ( J:211773 )

♂

IMPC - HAR

limb grasping ( J:211773 )

IMPC - HAR

tremors ( J:211773 )

♂

IMPC - HAR

abnormal gait ( J:211773 )

IMPC - HAR

decreased locomotor activity ( J:211773 )

♂

IMPC - HAR

homeostasis/metabolism

increased circulating phosphate level ( J:211773 )

♀

IMPC - HAR

limbs/digits/tail

abnormal digit morphology ( J:211773 )

IMPC - HAR

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:6480525

ht2

• Allelic Composition: Ngfr^{tm1b(EUCOMM)Wtsi}/Ngfr⁺
• Genetic Background: C57BL/6N-Ngfr^{tm1b(EUCOMM)Wtsi}/H
• Cell Lines: EPD0059_4_D03

Data Sources

IMPC Data for Ngfr

behavior/neurological

limb grasping ( J:211773 )

IMPC - HAR