Phenotypes associated with this allele

• Allele Symbol: Ntrk2^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5637214
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ntrk2^tm1b(EUCOMM)Wtsi/Ntrk2^tm1b(EUCOMM)Wtsi	C57BL/6N-Ntrk2^tm1b(EUCOMM)Wtsi/H	MGI:5757438
ht2	Ntrk2^tm1b(EUCOMM)Wtsi/Ntrk2^+	C57BL/6N-Ntrk2^tm1b(EUCOMM)Wtsi/H	MGI:5757437

Genotype
MGI:5757438

hm1

• Allelic Composition: Ntrk2^{tm1b(EUCOMM)Wtsi}/Ntrk2^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Ntrk2^{tm1b(EUCOMM)Wtsi}/H
• Cell Lines: EPD0591_5_A03

Data Sources

IMPC Data for Ntrk2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:5757437

ht2

• Allelic Composition: Ntrk2^{tm1b(EUCOMM)Wtsi}/Ntrk2⁺
• Genetic Background: C57BL/6N-Ntrk2^{tm1b(EUCOMM)Wtsi}/H
• Cell Lines: EPD0591_5_A03

Data Sources

IMPC Data for Ntrk2

growth/size/body

increased lean body mass ( J:211773 )

♂

IMPC - HAR

homeostasis/metabolism

increased circulating HDL cholesterol level ( J:211773 )

♀

IMPC - HAR

nervous system

decreased prepulse inhibition ( J:211773 )

♂

IMPC - HAR

skeleton

abnormal rib morphology ( J:211773 )

♀

IMPC - HAR