Phenotypes associated with this allele

• Allele Symbol: Magoh^{tm1d(KOMP)Dlsi}
• Allele Name: targeted mutation 1d, Debra L Silver
• Allele ID: MGI:5638556
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Magoh^tm1d(KOMP)Dlsi/Magoh^+	involves: C57BL/6J * FVB	MGI:5695295

Genotype
MGI:5695295

ht1

• Allelic Composition: Magoh^{tm1d(KOMP)Dlsi}/Magoh⁺
• Genetic Background: involves: C57BL/6J * FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

mortality/aging ( J:213515 )

N • heterozygotes are viable, unlike mice heterozygous for the Magoh^Mos2 allele which show partial postnatal lethality on a C57BL/6J background

nervous system

decreased brain size ( J:213515 )

• heterozygotes display smaller brain size at E16.5

thin cerebral cortex ( J:213515 )

• at E16.5, cortical thickness is significantly reduced relative to wild-type controls, although to a slightly lesser extent than in mice heterozygous for the Magoh^Mos2 allele

pigmentation

belly spot ( J:213515 )

• adult heterozygotes exhibit white belly spots

hypopigmentation ( J:213515 )

• adult heterozygotes exhibit ventral and dorsal hypopigmentation, similar to adult mice heterozygous for the Magoh^Mos2 allele

integument

belly spot ( J:213515 )

• adult heterozygotes exhibit white belly spots