Phenotypes associated with this allele

• Allele Symbol: Csk^{tm2b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 2b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5638576
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Csk^tm2b(EUCOMM)Hmgu/Csk^tm2b(EUCOMM)Hmgu	C57BL/6N-Csk^tm2b(EUCOMM)Hmgu/Bay	MGI:6262214
ht2	Csk^tm2b(EUCOMM)Hmgu/Csk^+	C57BL/6N-Csk^tm2b(EUCOMM)Hmgu/Bay	MGI:6370395

Genotype
MGI:6262214

hm1

• Allelic Composition: Csk^{tm2b(EUCOMM)Hmgu}/Csk^{tm2b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Csk^{tm2b(EUCOMM)Hmgu}/Bay
• Cell Lines: HEPD0640_2_A05

Data Sources

IMPC Data for Csk

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal embryo development ( J:211773 )

IMPC - BCM

abnormal embryo turning ( J:211773 )

IMPC - BCM

embryonic growth retardation ( J:211773 )

IMPC - BCM

abnormal embryo size ( J:211773 )

IMPC - BCM

abnormal neural tube closure ( J:211773 )

IMPC - BCM

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - BCM

abnormal embryo size ( J:211773 )

IMPC - BCM

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - BCM

preweaning lethality, complete penetrance ( J:211773 )

IMPC - BCM

nervous system

abnormal neural tube closure ( J:211773 )

IMPC - BCM

Genotype
MGI:6370395

ht2

• Allelic Composition: Csk^{tm2b(EUCOMM)Hmgu}/Csk⁺
• Genetic Background: C57BL/6N-Csk^{tm2b(EUCOMM)Hmgu}/Bay
• Cell Lines: HEPD0640_2_A05

Data Sources

IMPC Data for Csk

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

IMPC - BCM

vision/eye

abnormal retina vasculature morphology ( J:211773 )

IMPC - BCM

abnormal retina inner nuclear layer morphology ( J:211773 )

♀

IMPC - BCM

decreased total retina thickness ( J:211773 )

IMPC - BCM