Phenotypes associated with this allele

• Allele Symbol: Rab21^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5638577
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rab21^tm1b(KOMP)Wtsi/Rab21^tm1b(KOMP)Wtsi	C57BL/6N-Rab21^tm1b(KOMP)Wtsi/Wtsi	MGI:6263296

Genotype
MGI:6263296

hm1

• Allelic Composition: Rab21^{tm1b(KOMP)Wtsi}/Rab21^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Rab21^{tm1b(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0586_2_H10

Data Sources

IMPC Data for Rab21

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal chorion morphology ( J:261316 )

• unpatterned chorion at E9.5

abnormal placenta morphology ( J:261316 )

• branching morphology defect at E9.5

abnormal trophoblast layer morphology ( J:261316 )

• small or absent trophoblast compartment at E9.5

• biased differentiation (diploid/polyploid trophoblast)

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - WTSI

lethality throughout fetal growth and development, complete penetrance ( J:261316 )

• complete lethality at E14.5