Phenotypes associated with this allele

• Allele Symbol: Coq8b^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5638687
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Coq8b^tm1b(EUCOMM)Hmgu/Coq8b^tm1b(EUCOMM)Hmgu	B6N(Cg)-Coq8b^tm1b(EUCOMM)Hmgu/J	MGI:6262192
ht2	Coq8b^tm1b(EUCOMM)Hmgu/Coq8b^+	B6N(Cg)-Coq8b^tm1b(EUCOMM)Hmgu/J	MGI:6262191

Genotype
MGI:6262192

hm1

• Allelic Composition: Coq8b^{tm1b(EUCOMM)Hmgu}/Coq8b^{tm1b(EUCOMM)Hmgu}
• Genetic Background: B6N(Cg)-Coq8b^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0748_8_F07

Data Sources

IMPC Data for Coq8b

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - JAX

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:6262191

ht2

• Allelic Composition: Coq8b^{tm1b(EUCOMM)Hmgu}/Coq8b⁺
• Genetic Background: B6N(Cg)-Coq8b^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0748_8_F07

Data Sources

IMPC Data for Coq8b

behavior/neurological

decreased locomotor activity ( J:211773 )

♀

IMPC - JAX

hematopoietic system

decreased mean corpuscular hemoglobin concentration ( J:211773 )

♂

IMPC - JAX

homeostasis/metabolism

decreased fasting circulating glucose level ( J:211773 )

♂

IMPC - JAX

impaired glucose tolerance ( J:211773 )

♂

IMPC - JAX

skeleton

decreased bone mineral content ( J:211773 )

IMPC - JAX