Phenotypes associated with this allele

• Allele Symbol: Ap1g1^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5638688
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ap1g1^tm1b(EUCOMM)Hmgu/Ap1g1^tm1b(EUCOMM)Hmgu	B6N(Cg)-Ap1g1^tm1b(EUCOMM)Hmgu/J	MGI:6261876
ht2	Ap1g1^tm1b(EUCOMM)Hmgu/Ap1g1^+	B6N(Cg)-Ap1g1^tm1b(EUCOMM)Hmgu/J	MGI:6261875

Genotype
MGI:6261876

hm1

• Allelic Composition: Ap1g1^{tm1b(EUCOMM)Hmgu}/Ap1g1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: B6N(Cg)-Ap1g1^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0677_1_C11

Data Sources

IMPC Data for Ap1g1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:6261875

ht2

• Allelic Composition: Ap1g1^{tm1b(EUCOMM)Hmgu}/Ap1g1⁺
• Genetic Background: B6N(Cg)-Ap1g1^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0677_1_C11

Data Sources

IMPC Data for Ap1g1

adipose tissue

increased total body fat amount ( J:211773 )

♀

IMPC - JAX

behavior/neurological

hyperactivity ( J:211773 )

IMPC - JAX

increased vertical activity ( J:211773 )

♀

IMPC - JAX

growth/size/body

decreased lean body mass ( J:211773 )

♀

IMPC - JAX

nervous system

abnormal optic disk morphology ( J:211773 )

IMPC - JAX

skeleton

decreased bone mineral content ( J:211773 )

♀

IMPC - JAX

vision/eye

abnormal optic disk morphology ( J:211773 )

IMPC - JAX

cataract ( J:211773 )

♂

IMPC - JAX

abnormal retina morphology ( J:211773 )

♀

IMPC - JAX