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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rb1tm3Fad
targeted mutation 3, Frederick A Dick
MGI:5638883
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rb1tm3Fad/Rb1tm3Fad involves: 129S1/Sv * 129X1/SvJ MGI:6401097


Genotype
MGI:6401097
hm1
Allelic
Composition		 Rb1tm3Fad/Rb1tm3Fad
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rb1tm3Fad mutation (1 available); any Rb1 mutation (111 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
decreased tumor-free survival time ( J:249124 )
• mice exhibit reduced tumor-free survival, with a median lifespan of 576 days

neoplasm
increased lymphoma incidence ( J:249124 )
• majority of mice succumb to lymphomas, particularly in the spleen and mesenteric lymph node




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory