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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ccr7m1Btlr
mutation 1, Bruce Beutler
MGI:5640785
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ccr7m1Btlr/Ccr7m1Btlr C57BL/6J-Ccr7m1Btlr MGI:5641222
ht2
Ccr7m1Btlr/Ccr7+ C57BL/6J-Ccr7m1Btlr MGI:5641223


Genotype
MGI:5641222
hm1
Allelic
Composition
Ccr7m1Btlr/Ccr7m1Btlr
Genetic
Background
C57BL/6J-Ccr7m1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccr7m1Btlr mutation (0 available); any Ccr7 mutation (29 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• mice exhibit an increase in the CD4+ to CD8+ T cell ratio in the peripheral blood caused by an increased frequency of CD4+ T cells
• some mice also exhibited a reduced frequency of macrophages in the peripheral blood

immune system
• mice exhibit an increase in the CD4+ to CD8+ T cell ratio in the peripheral blood caused by an increased frequency of CD4+ T cells
• some mice also exhibited a reduced frequency of macrophages in the peripheral blood




Genotype
MGI:5641223
ht2
Allelic
Composition
Ccr7m1Btlr/Ccr7+
Genetic
Background
C57BL/6J-Ccr7m1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccr7m1Btlr mutation (0 available); any Ccr7 mutation (29 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• some mice also exhibited a reduced frequency of macrophages in the peripheral blood

immune system
• some mice also exhibited a reduced frequency of macrophages in the peripheral blood





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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory