About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Sumo3tm1Weiy
targeted mutation 1, Wei Yang
MGI:5641884
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Sumo3tm1Weiy/Sumo3tm1Weiy involves: 129 * C57BL/6 MGI:5641951
ht2
 		Sumo3tm1Weiy/Sumo3+ involves: 129 * C57BL/6 MGI:5690068
cx3
 		Sumo2tm1Weiy/Sumo2+
Sumo3tm1Weiy/Sumo3+ 		involves: 129 * C57BL/6 MGI:5690071
cx4
 		Sumo2tm1Weiy/Sumo2+
Sumo3tm1Weiy/Sumo3tm1Weiy 		involves: 129 * C57BL/6 MGI:5690075


Genotype
MGI:5641951
hm1
Allelic
Composition		 Sumo3tm1Weiy/Sumo3tm1Weiy
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sumo3tm1Weiy mutation (1 available); any Sumo3 mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:217019 )
• homozygotes are viable and fertile and exhibit no phenotypic abnormalities




Genotype
MGI:5690068
ht2
Allelic
Composition		 Sumo3tm1Weiy/Sumo3+
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sumo3tm1Weiy mutation (1 available); any Sumo3 mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:217019 )
• heterozygotes are viable and fertile and exhibit no gross abnormalities in size or weight relative to wild-type littermate controls




Genotype
MGI:5690071
cx3
Allelic
Composition		 Sumo2tm1Weiy/Sumo2+
Sumo3tm1Weiy/Sumo3+
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sumo2tm1Weiy mutation (1 available); any Sumo2 mutation (16 available)
Sumo3tm1Weiy mutation (1 available); any Sumo3 mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:217019 )
• double heterozygotes are viable and display no overt phenotype




Genotype
MGI:5690075
cx4
Allelic
Composition		 Sumo2tm1Weiy/Sumo2+
Sumo3tm1Weiy/Sumo3tm1Weiy
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sumo2tm1Weiy mutation (1 available); any Sumo2 mutation (16 available)
Sumo3tm1Weiy mutation (1 available); any Sumo3 mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
lethality throughout fetal growth and development, incomplete penetrance ( J:217019 )
• only 2 mutant mice are found at birth in 35 litters after crossing mice that are double heterozygous for Sumo2tm1Weiy and Sumo3tm1Weiy with Sumo3tm1Weiy homozygotes

growth/size/body
decreased birth body size ( J:217019 )
• although mutant mice show no overt phenotype at E15.5 and E17.5, they are considerably smaller than Sumo3tm1Weiy homozygotes at birth (E19.5)
decreased body size ( J:217019 )
• at P10, mutant mice are significantly smaller than Sumo3tm1Weiy homozygotes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory