Phenotypes associated with this allele

• Allele Symbol: Cog7^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5642366
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cog7^tm1b(EUCOMM)Hmgu/Cog7^tm1b(EUCOMM)Hmgu	B6N(Cg)-Cog7^tm1b(EUCOMM)Hmgu/J	MGI:6262184
ht2	Cog7^tm1b(EUCOMM)Hmgu/Cog7^+	B6N(Cg)-Cog7^tm1b(EUCOMM)Hmgu/J	MGI:6461168

Genotype
MGI:6262184

hm1

• Allelic Composition: Cog7^{tm1b(EUCOMM)Hmgu}/Cog7^{tm1b(EUCOMM)Hmgu}
• Genetic Background: B6N(Cg)-Cog7^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0681_4_B12

Data Sources

IMPC Data for Cog7

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:6461168

ht2

• Allelic Composition: Cog7^{tm1b(EUCOMM)Hmgu}/Cog7⁺
• Genetic Background: B6N(Cg)-Cog7^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0681_4_B12

Data Sources

IMPC Data for Cog7

behavior/neurological

impaired pupillary reflex ( J:211773 )

♀

IMPC - JAX

cardiovascular system

abnormal sinus arrhythmia ( J:211773 )

♀

IMPC - JAX

vision/eye

impaired pupillary reflex ( J:211773 )

♀

IMPC - JAX

cornea deposits ( J:211773 )

♀

IMPC - JAX