About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
NipblGt(EUCE313f02)1.2Hmgu
gene trap EUCE313f02, 1.2, Helmholtz Zentrum Muenchen GmbH
MGI:5644813
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
NipblGt(EUCE313f02)1.2Hmgu/Nipbl+ involves: 129 * C57BL/6J * FVB/N MGI:7490421
ht2
NipblGt(EUCE313f02)1.2Hmgu/Nipbl+ involves: 129P2/OlaHsd * CD-1 MGI:7492204
cx3
NipblGt(EUCE313f02)1.2Hmgu/Nipbl+
Wapltm1.2Kpfe/Wapl+
involves: 129 * C57BL/6J * FVB/N MGI:7444073
cx4
NipblGt(EUCE313f02)1.2Hmgu/Nipbl+
Wapltm1.1Kpfe/Wapltm1.2Kpfe
involves: 129 * C57BL/6J * FVB/N MGI:7490411


Genotype
MGI:7490421
ht1
Allelic
Composition
NipblGt(EUCE313f02)1.2Hmgu/Nipbl+
Genetic
Background
involves: 129 * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
NipblGt(EUCE313f02)1.2Hmgu mutation (0 available); any Nipbl mutation (124 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
embryo

growth/size/body




Genotype
MGI:7492204
ht2
Allelic
Composition
NipblGt(EUCE313f02)1.2Hmgu/Nipbl+
Genetic
Background
involves: 129P2/OlaHsd * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
NipblGt(EUCE313f02)1.2Hmgu mutation (0 available); any Nipbl mutation (124 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

cardiovascular system
• at E17.5 in about 30% of mice
• however, no ventricular septal defect, arterial stenosis or obvious abnormalities of ventricular wall thickness are seen
• in proportion to decrease in body size

growth/size/body




Genotype
MGI:7444073
cx3
Allelic
Composition
NipblGt(EUCE313f02)1.2Hmgu/Nipbl+
Wapltm1.2Kpfe/Wapl+
Genetic
Background
involves: 129 * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
NipblGt(EUCE313f02)1.2Hmgu mutation (0 available); any Nipbl mutation (124 available)
Wapltm1.2Kpfe mutation (0 available); any Wapl mutation (169 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
embryo
• embryos are significantly larger than mutant mice wild-type for Wapl
• partial rescue of about 24% of reduced embryo growth phenotype

mortality/aging

growth/size/body
• embryos are significantly larger than mutant mice wild-type for Wapl
• partial rescue of about 24% of reduced embryo growth phenotype




Genotype
MGI:7490411
cx4
Allelic
Composition
NipblGt(EUCE313f02)1.2Hmgu/Nipbl+
Wapltm1.1Kpfe/Wapltm1.2Kpfe
Genetic
Background
involves: 129 * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
NipblGt(EUCE313f02)1.2Hmgu mutation (0 available); any Nipbl mutation (124 available)
Wapltm1.1Kpfe mutation (1 available); any Wapl mutation (169 available)
Wapltm1.2Kpfe mutation (0 available); any Wapl mutation (169 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
embryo
• embryos are significantly larger than mutant mice wild-type for Wapl
• partial rescue of about 24% of reduced embryo growth phenotype

mortality/aging

growth/size/body
• embryos are significantly larger than mutant mice wild-type for Wapl
• partial rescue of about 24% of reduced embryo growth phenotype





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory