Analysis Tools|
Allele Symbol Allele Name Allele ID |
NipblGt(EUCE313f02)1.2Hmgu gene trap EUCE313f02, 1.2, Helmholtz Zentrum Muenchen GmbH MGI:5644813 |
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| Summary |
4 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• survive poorly
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• at E17.5 in about 30% of mice
• however, no ventricular septal defect, arterial stenosis or obvious abnormalities of ventricular wall thickness are seen
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• in proportion to decrease in body size
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• embryos are significantly larger than mutant mice wild-type for Wapl
• partial rescue of about 24% of reduced embryo growth phenotype
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• none found at weaning
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• embryos are significantly larger than mutant mice wild-type for Wapl
• partial rescue of about 24% of reduced embryo growth phenotype
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• embryos are significantly larger than mutant mice wild-type for Wapl
• partial rescue of about 24% of reduced embryo growth phenotype
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• none found at weaning
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• embryos are significantly larger than mutant mice wild-type for Wapl
• partial rescue of about 24% of reduced embryo growth phenotype
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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