All Phenotypes Prickle1<tm1Asw> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Prickle1^tm1Asw
targeted mutation 1, Anand Swaroop
MGI:5645929

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prickle1^tm1Asw/Prickle1^tm1Asw	Not Specified	MGI:5648842
ht2	Prickle1^tm1Asw/Prickle1^tm1.2Asw	Not Specified	MGI:5648857

Allelic Composition	Prickle1^tm1Asw/Prickle1^tm1Asw
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prickle1^tm1Asw mutation (0 available); any Prickle1 mutation (34 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

fused lower incisors ( J:213772 )

• fused mandibular incisors

prominent forehead ( J:213772 )

flattened snout ( J:213772 )

• flat nose

short snout ( J:213772 )

growth/size/body

fused lower incisors ( J:213772 )

• fused mandibular incisors

prominent forehead ( J:213772 )

flattened snout ( J:213772 )

• flat nose

short snout ( J:213772 )

decreased body length ( J:213772 )

limbs/digits/tail

brachydactyly ( J:213772 )

• shortened digital bones

skeleton

fused lower incisors ( J:213772 )

• fused mandibular incisors

decreased length of long bones ( J:213772 )

• shortened long bones and digital bones

abnormal vertebrae development ( J:213772 )

• incomplete and distorted vertebrae formation in the spinal cord

vision/eye

ocular hypertelorism ( J:213772 )

abnormal eyelid morphology ( J:213772 )

• abnormal appearance of eyelid and eyelashes

abnormal eyelid cilium morphology ( J:213772 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
autosomal recessive Robinow syndrome		DOID:0060764	OMIM:268310	J:213772

Allelic Composition	Prickle1^tm1Asw/Prickle1^tm1.2Asw
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prickle1^tm1.2Asw mutation (0 available); any Prickle1 mutation (34 available)
Prickle1^tm1Asw mutation (0 available); any Prickle1 mutation (34 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

fused lower incisors ( J:213772 )

• fused mandibular incisors

prominent forehead ( J:213772 )

flattened snout ( J:213772 )

• flat nose

short snout ( J:213772 )

growth/size/body

fused lower incisors ( J:213772 )

• fused mandibular incisors

prominent forehead ( J:213772 )

flattened snout ( J:213772 )

• flat nose

short snout ( J:213772 )

decreased body length ( J:213772 )

limbs/digits/tail

brachydactyly ( J:213772 )

• shortened digital bones

kinked tail ( J:213772 )

skeleton

fused lower incisors ( J:213772 )

• fused mandibular incisors

decreased length of long bones ( J:213772 )

• shortened long bones and digital bones

abnormal vertebrae development ( J:213772 )

• incomplete and distorted vertebrae formation in the spinal cord

vision/eye

ocular hypertelorism ( J:213772 )

abnormal eyelid morphology ( J:213772 )

• abnormal appearance of eyelid and eyelashes

abnormal eyelid cilium morphology ( J:213772 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
autosomal recessive Robinow syndrome		DOID:0060764	OMIM:268310	J:213772

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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