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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Prickle1tm1.3Asw
targeted mutation 1.3, Anand Swaroop
MGI:5645933
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Prickle1tm1.3Asw/Prickle1tm1.3Asw
Edil3Tg(Sox2-cre)1Amc/Edil3+ 		involves: C57BL/6 * CBA MGI:5649031
cn2
 		Prickle1tm1.2Asw/Prickle1tm1.3Asw
Edil3Tg(Sox2-cre)1Amc/Edil3+ 		involves: C57BL/6 * CBA MGI:5649032


Genotype
MGI:5649031
cn1
Allelic
Composition		 Prickle1tm1.3Asw/Prickle1tm1.3Asw
Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic
Background		 involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Edil3Tg(Sox2-cre)1Amc mutation (5 available); any Edil3 mutation (43 available)
Prickle1tm1.3Asw mutation (0 available); any Prickle1 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, complete penetrance ( J:213772 )
• mice survive until around P4




Genotype
MGI:5649032
cn2
Allelic
Composition		 Prickle1tm1.2Asw/Prickle1tm1.3Asw
Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic
Background		 involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Edil3Tg(Sox2-cre)1Amc mutation (5 available); any Edil3 mutation (43 available)
Prickle1tm1.2Asw mutation (0 available); any Prickle1 mutation (34 available)
Prickle1tm1.3Asw mutation (0 available); any Prickle1 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
abnormal hair follicle development ( J:213772 )
• mice exhibit midline hair follicle development defects at P3
abnormal hair follicle orientation ( J:213772 )
• mice exhibit midline hair follicle orientation defects at P3




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory