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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tm59
mutation Tm59
MGI:5646555
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ot1
 		Tm59/? involves: C3H/HeH * C57BL/6J MGI:5646556


Genotype
MGI:5646556
ot1
Allelic
Composition		 Tm59/?
Genetic
Background		 involves: C3H/HeH * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tm59 mutation (2 available); any Tm59 mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
increased body weight ( J:169366 )
• significantly heavier than wild type at 12 and 16 weeks of age

homeostasis/metabolism
increased circulating insulin level ( J:169366 )
• fasting hyperinsulinaemia at 16 weeks
abnormal glucose tolerance ( J:169366 )
• abnormal response to Intraperitoneal Glucose Tolerance Test at 12 weeks of age




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory