Phenotypes associated with this allele

• Allele Symbol: Stra6^tm1Jvli
• Allele Name: targeted mutation 1, Johannes Von Lintig
• Allele ID: MGI:5648726
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Stra6^tm1Jvli/Stra6^tm1Jvli	involves: C57BL/6	MGI:5659945

Genotype
MGI:5659945

hm1

• Allelic Composition: Stra6^tm1Jvli/Stra6^tm1Jvli
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal cranium morphology ( J:214659 )

• rounded cranium

enlarged cranium ( J:214659 )

growth/size/body

decreased body size ( J:214659 )

• very small body size

decreased body weight ( J:214659 )

• mice have low weight and fail to thrive

mortality/aging

postnatal lethality, complete penetrance ( J:214659 )

• mice die around weaning time

nervous system

hydrocephaly ( J:214659 )

• mice develop progressive hydrocephalus

dilated brain ventricle ( J:214659 )

• swelling of the brain ventricles is already seen in 2 day old mice, progresses in 10 day old mice such that damage is seen in the corpus callosum, and by P21, swelling of the ventricular system leads to gross damage to the brain area

skeleton

abnormal cranium morphology ( J:214659 )

• rounded cranium

enlarged cranium ( J:214659 )