All Phenotypes U2af1l4<tm1.2Tmo> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

U2af1l4^tm1.2Tmo
targeted mutation 1.2, Tarik Moroy
MGI:5659888

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	U2af1l4^tm1.2Tmo/U2af1l4^tm1.2Tmo	B6.Cg-U2af1l4^tm1.2Tmo	MGI:5659891

Allelic Composition	U2af1l4^tm1.2Tmo/U2af1l4^tm1.2Tmo
Genetic Background	B6.Cg-U2af1l4^tm1.2Tmo

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
U2af1l4^tm1.2Tmo mutation (0 available); any U2af1l4 mutation (10 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal circardian behavior entrainment ( J:215244 )

• expression of PER1 is nearly arrhythmic

• in a 4 phase-advance assay, mice adapt to the time change more rapidly adjusting the onset of activity by over 3h on the first day compared to about 1h for wild-type controls

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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