Phenotypes associated with this allele

• Allele Symbol: Col1a1^{tm5(CAG-FGFR2_iIIIb*W290C)Kkw}
• Allele Name: targeted mutation 5, Kwok-Kin Wong
• Allele ID: MGI:5661327
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Col1a1^tm5(CAG-FGFR2_iIIIb*W290C)Kkw/Col1a1^+ Trp53^tm1Brn/Trp53^tm1Brn	involves: 129P2/OlaHsd * 129S4/SvJae * BALB/c * C57BL/6	MGI:5661331

Genotype
MGI:5661331

cn1

• Allelic Composition: Col1a1^{tm5(CAG-FGFR2_iIIIb*W290C)Kkw}/Col1a1⁺; Trp53^tm1Brn/Trp53^tm1Brn
• Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * BALB/c * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased lung tumor incidence ( J:214230 )

• mice develop lung tumors with a longer latency than seen in Col1a1^{tm4(CAG-FGFR2_iIIIb*K660N)Kkw} mice after intranasal delivery of an adenovirus expressing cre recombinase, with a penetrance of 35%

respiratory system

increased lung tumor incidence ( J:214230 )

• mice develop lung tumors with a longer latency than seen in Col1a1^{tm4(CAG-FGFR2_iIIIb*K660N)Kkw} mice after intranasal delivery of an adenovirus expressing cre recombinase, with a penetrance of 35%

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
lung cancer		DOID:1324	OMIM:211980 OMIM:608935 OMIM:612571 OMIM:612593 OMIM:614210	J:214230