Phenotypes associated with this allele

• Allele Symbol: Pax3^Rwa
• Allele Name: Riken white A
• Allele ID: MGI:5662101
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pax3^Rwa/Pax3^Rwa	B6N.Cg-Pax3^Rwa	MGI:5906272
ht2	Pax3^Rwa/Pax3^+	B6N.Cg-Pax3^Rwa	MGI:5906271

Genotype
MGI:5906272

hm1

• Allelic Composition: Pax3^Rwa/Pax3^Rwa
• Genetic Background: B6N.Cg-Pax3^Rwa

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal embryo morphology ( J:241031 )

• embryos malformed at E15

decreased embryo size ( J:241031 )

• embryos much smaller than wild-type littermates at E10.5 and E15

open neural tube ( J:241031 )

• closure defect at E10.5-11.5

growth/size/body

decreased embryo size ( J:241031 )

• embryos much smaller than wild-type littermates at E10.5 and E15

mortality/aging

embryonic lethality ( J:241031 )

• no homozygotes are born

nervous system

open neural tube ( J:241031 )

• closure defect at E10.5-11.5

Genotype
MGI:5906271

ht2

• Allelic Composition: Pax3^Rwa/Pax3⁺
• Genetic Background: B6N.Cg-Pax3^Rwa

embryo

spina bifida ( J:241031 )

• in caudal region of E18.5 embryos

integument

abnormal hind foot hair pigmentation ( J:241031 )

• unpigmented toes

abnormal tail hair pigmentation ( J:241031 )

• unpigmented spots or bands

abnormal ventral coat pigmentation ( J:241031 )

• white belly spot

transverse fur striping ( J:241031 )

• white dorsal stripe

belly spot ( J:241031 )

• white spot

limbs/digits/tail

curly tail ( J:241031 )

nervous system

spina bifida ( J:241031 )

• in caudal region of E18.5 embryos

pigmentation

abnormal hind foot hair pigmentation ( J:241031 )

• unpigmented toes

abnormal tail hair pigmentation ( J:241031 )

• unpigmented spots or bands

abnormal ventral coat pigmentation ( J:241031 )

• white belly spot

transverse fur striping ( J:241031 )

• white dorsal stripe

belly spot ( J:241031 )

• white spot