Phenotypes associated with this allele

• Allele Symbol: Jak1^tm1.1Kuw
• Allele Name: targeted mutation 1.1, Kay-Uwe Wagner
• Allele ID: MGI:5688350
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Jak1^tm1.1Kuw/Jak1^tm1.1Kuw	involves: 129X1/SvJ * C57BL/6 * FVB	MGI:5796277

Genotype
MGI:5796277

hm1

• Allelic Composition: Jak1^tm1.1Kuw/Jak1^tm1.1Kuw
• Genetic Background: involves: 129X1/SvJ * C57BL/6 * FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:235355 )

• newborns show signs of apnea and die within 30 min to 2 hours after birth

growth/size/body

decreased fetal size ( J:235355 )

• embryos are smaller starting at E15.5

respiratory system

apnea ( J:235355 )

• pups at birth are gasping for air and intermittently exhibit longer pauses in breathing indicating signs of apnea