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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ccnytm1.1Smoc
targeted mutation 1.1, Shanghai Model Organisms Center
MGI:5688373
Summary 5 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ccnytm1.1Smoc/Ccnytm1.1Smoc involves: C57BL/6 MGI:5688380
hm2
Ccnytm1.1Smoc/Ccnytm1.1Smoc Not Specified MGI:5688386
cx3
Ccnytm1.1Smoc/Ccnytm1.1Smoc
Ccnyl1tm1a(EUCOMM)Wtsi/Ccnyl1+
involves: C57BL/6N MGI:5688388
cx4
Ccnytm1.1Smoc/Ccnytm1.1Smoc
Ccnyl1tm1a(EUCOMM)Wtsi/Ccnyl1tm1a(EUCOMM)Wtsi
involves: C57BL/6N MGI:5688387
cx5
Ccnytm1.1Smoc/Ccny+
Ccnyl1tm1a(EUCOMM)Wtsi/Ccnyl1tm1a(EUCOMM)Wtsi
involves: C57BL/6N MGI:5688389


Genotype
MGI:5688380
hm1
Allelic
Composition
Ccnytm1.1Smoc/Ccnytm1.1Smoc
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccnytm1.1Smoc mutation (0 available); any Ccny mutation (18 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
adipose tissue
N
• brown adipose weight is normal
• in mice fed standard chow or a calorically restricted diet
• impaired adipogenesis
• decreased retroperitoneal, inguinal, perirenal and arm-pit fat in mice fed standard chow or a high fat diet compared with wild-type mice
• in mice fed standard chow or a high fat diet
• in mice fed standard chow or a high fat diet
• in mice fed standard chow or a high fat diet
• mice exhibit higher activity of brown adipocytes compared with wild-type mice

homeostasis/metabolism
N
• mice exhibit normal glucose and insulin tolerance and fasting basal glucose and insulin levels
• in mice fed standard chow, a high fat diet or a calorically restricted diet
• in mice fed standard chow, a high fat diet or a calorically restricted diet
• in mice fed standard chow, a high fat diet or a calorically restricted diet
• in mice fed standard chow

growth/size/body
• after 5 weeks in mice fed standard chow
• at 14 weeks in mice fed standard chow
• in mice fed a high fat diet
• in mice fed a calorically restricted diet

behavior/neurological

cellular
• impaired adipogenesis

liver/biliary system
• in mice fed standard chow




Genotype
MGI:5688386
hm2
Allelic
Composition
Ccnytm1.1Smoc/Ccnytm1.1Smoc
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccnytm1.1Smoc mutation (0 available); any Ccny mutation (18 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• mice exhibit normal fertility with normal sperm counts and sperm motility




Genotype
MGI:5688388
cx3
Allelic
Composition
Ccnytm1.1Smoc/Ccnytm1.1Smoc
Ccnyl1tm1a(EUCOMM)Wtsi/Ccnyl1+
Genetic
Background
involves: C57BL/6N
Cell Lines EPD0177_5_F06
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccnyl1tm1a(EUCOMM)Wtsi mutation (2 available); any Ccnyl1 mutation (17 available)
Ccnytm1.1Smoc mutation (0 available); any Ccny mutation (18 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
N
• mice are born and survive into adulthood




Genotype
MGI:5688387
cx4
Allelic
Composition
Ccnytm1.1Smoc/Ccnytm1.1Smoc
Ccnyl1tm1a(EUCOMM)Wtsi/Ccnyl1tm1a(EUCOMM)Wtsi
Genetic
Background
involves: C57BL/6N
Cell Lines EPD0177_5_F06
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccnyl1tm1a(EUCOMM)Wtsi mutation (2 available); any Ccnyl1 mutation (17 available)
Ccnytm1.1Smoc mutation (0 available); any Ccny mutation (18 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:5688389
cx5
Allelic
Composition
Ccnytm1.1Smoc/Ccny+
Ccnyl1tm1a(EUCOMM)Wtsi/Ccnyl1tm1a(EUCOMM)Wtsi
Genetic
Background
involves: C57BL/6N
Cell Lines EPD0177_5_F06
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccnyl1tm1a(EUCOMM)Wtsi mutation (2 available); any Ccnyl1 mutation (17 available)
Ccnytm1.1Smoc mutation (0 available); any Ccny mutation (18 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
N
• mice are born and survive into adulthood





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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory