All Phenotypes Fasl<m2Btlr> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Fasl^m2Btlr
mutation 2, Bruce Beutler
MGI:5688496

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fasl^m2Btlr/Fasl^m2Btlr	C57BL/6J-Fasl^m2Btlr	MGI:5688547

Allelic Composition	Fasl^m2Btlr/Fasl^m2Btlr
Genetic Background	C57BL/6J-Fasl^m2Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fasl^m2Btlr mutation (0 available); any Fasl mutation (37 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased IgG level ( J:224659 )

• mice exhibited diminished T-dependent antibody response to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)

impaired humoral immune response ( J:224659 )

• mice exhibited diminished T-dependent antibody response to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)

hematopoietic system

decreased IgG level ( J:224659 )

• mice exhibited diminished T-dependent antibody response to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/22/2024 MGI 6.24