Phenotypes associated with this allele

• Allele Symbol: Cd22^m4Btlr
• Allele Name: mutation 4, Bruce Beutler
• Allele ID: MGI:5688497
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cd22^m4Btlr/Cd22^m4Btlr	C57BL/6J-Cd22^m4Btlr	MGI:5688543

Genotype
MGI:5688543

hm1

• Allelic Composition: Cd22^m4Btlr/Cd22^m4Btlr
• Genetic Background: C57BL/6J-Cd22^m4Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

increased B-1a cell number ( J:224660 )

• an increased frequency of B1a cells

• an increased frequency of B1a cells in B1 cells

decreased B cell number ( J:224660 )

• decreased in the B:T cell ratio caused by a diminished frequency of B cells

• all in the peripheral blood

decreased B-2 B cell number ( J:224660 )

decreased memory B cell number ( J:224660 )

• a reduced frequency of IgM+ B cells

• a decreased percentage of IgD+ B cells

hematopoietic system

increased B-1a cell number ( J:224660 )

• an increased frequency of B1a cells

• an increased frequency of B1a cells in B1 cells

decreased B cell number ( J:224660 )

• decreased in the B:T cell ratio caused by a diminished frequency of B cells

• all in the peripheral blood

decreased B-2 B cell number ( J:224660 )

decreased memory B cell number ( J:224660 )

• a reduced frequency of IgM+ B cells

• a decreased percentage of IgD+ B cells