All Phenotypes Prkdc<m3Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Prkdc^m3Btlr
mutation 3, Bruce Beutler
MGI:5688503

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prkdc^m3Btlr/Prkdc^m3Btlr	C57BL/6J-Prkdc^m3Btlr	MGI:5688629

Allelic Composition	Prkdc^m3Btlr/Prkdc^m3Btlr
Genetic Background	C57BL/6J-Prkdc^m3Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prkdc^m3Btlr mutation (0 available); any Prkdc mutation (417 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased IgG level ( J:224665 )

• mice show a diminished T-dependent antibody response to ovalbumin (OVA) administered with aluminum hydroxide

impaired humoral immune response ( J:224665 )

• mice show a diminished T-dependent antibody response to ovalbumin (OVA) administered with aluminum hydroxide

hematopoietic system

decreased IgG level ( J:224665 )

• mice show a diminished T-dependent antibody response to ovalbumin (OVA) administered with aluminum hydroxide

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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