Phenotypes associated with this allele

• Allele Symbol: Rxfp3^tm1Dgen
• Allele Name: targeted mutation 1, Deltagen
• Allele ID: MGI:5688755
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rxfp3^tm1Dgen/Rxfp3^tm1Dgen	B6.Cg-Rxfp3^tm1Dgen	MGI:5688759

Genotype
MGI:5688759

hm1

• Allelic Composition: Rxfp3^tm1Dgen/Rxfp3^tm1Dgen
• Genetic Background: B6.Cg-Rxfp3^tm1Dgen

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:216975 )

N • no notable motor deficits are detected in rotarod assays

N • no abnormalities in novel object recognition, startle response or forced swim behavior are detected

decreased anxiety-related response ( J:216975 )

• males but not females make more entries into the open arms of an elevated plus maze compared to sex-matched wild-type controls

• mice spend more time in the aversive light side of a light/dark box and this effect is more pronounced in females than males compared to sex-matched wild-type controls

• however, no differences in center vs edge time were seen in a large open field assay compared to controls

decreased locomotor activity ( J:216975 )

• decreased activity on voluntary home-cage running wheels in males and females

growth/size/body

growth/size/body region phenotype ( J:216975 )

N • no difference in body weight from controls at 8 and 16 weeks of age