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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Del(16Setd4-Kcnj6)12Yey
deletion, Chr 16, Y Eugene Yu 12
MGI:5689383
Summary 2 genotypes


Genotype
MGI:5690033
ht1
Allelic
Composition
Del(16Setd4-Kcnj6)12Yey/+
Genetic
Background
B6.129S7-Del(16Setd4-Kcnj6)12Yey
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(16Setd4-Kcnj6)12Yey mutation (1 available); any Del(16Setd4-Kcnj6)12Yey mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• deletion is transmitted at a ratio that is lower than expected




Genotype
MGI:5690031
cx2
Allelic
Composition
Del(16Setd4-Kcnj6)12Yey/Dp(16Lipi-Zbtb21)1Yey
Genetic
Background
B6.129S7-Del(16Setd4-Kcnj6)12Yey/Dp(16Lipi-Zbtb21)1Yey
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(16Setd4-Kcnj6)12Yey mutation (1 available); any Del(16Setd4-Kcnj6)12Yey mutation (1 available)
Dp(16Lipi-Zbtb21)1Yey mutation (3 available); any Dp(16Lipi-Zbtb21)1Yey mutation (3 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mice exhibit decreased freezing behavior in contextual fear-conditioning test as compared to wild type
• impaired performance in T maze spontaneous alteration test as compared to controls

nervous system
• magnitude of hippocampal LTP following theta burst stimulation is lower than controls





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
08/02/2024
MGI 6.24
The Jackson Laboratory