About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nos3m1Btlr
mutation 1, Bruce Beutler
MGI:5691955
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nos3m1Btlr/Nos3m1Btlr C57BL/6J-Nos3m1Btlr MGI:5692063


Genotype
MGI:5692063
hm1
Allelic
Composition		 Nos3m1Btlr/Nos3m1Btlr
Genetic
Background		 C57BL/6J-Nos3m1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nos3m1Btlr mutation (0 available); any Nos3 mutation (56 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
increased susceptibility to induced colitis ( J:225268 )
• mice are susceptible to low doses of DSS (1%) and show weight loss seven days after DSS treatment

growth/size/body
increased susceptibility to weight loss ( J:225268 )
• mice are susceptible to low doses of DSS (1%) and show weight loss seven days after DSS treatment

immune system
increased susceptibility to induced colitis ( J:225268 )
• mice are susceptible to low doses of DSS (1%) and show weight loss seven days after DSS treatment




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
07/05/2024
MGI 6.24 		The Jackson Laboratory