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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Sycp2ltm1Jw
targeted mutation 1, Jeremy Wang
MGI:5692068
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Sycp2ltm1Jw/Sycp2ltm1Jw involves: 129S4/SvJae * C57BL/6 MGI:5692282


Genotype
MGI:5692282
hm1
Allelic
Composition
Sycp2ltm1Jw/Sycp2ltm1Jw
Genetic
Background
involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sycp2ltm1Jw mutation (1 available); any Sycp2l mutation (30 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• progressive reduction of primordial oocytes as compared to controls
• oocyte numbers are similar to controls at 10 days of age, but drop to 20% of controls at 14 months

reproductive system
• progressive reduction of primordial oocytes as compared to controls
• oocyte numbers are similar to controls at 10 days of age, but drop to 20% of controls at 14 months
• number of primary follicles is reduced at 12 months of age as compared to controls
• number of primordial follicles is reduced at 2 months, 8 months and 12 months as compared to controls
• number of secondary follicles is reduced at 12 months of age as compared to controls
• females show accelerated reproductive aging
• litter sizes are reduced , however number of litters is similar to controls

mortality/aging
• females show accelerated reproductive aging

endocrine/exocrine glands
• number of primary follicles is reduced at 12 months of age as compared to controls
• number of primordial follicles is reduced at 2 months, 8 months and 12 months as compared to controls
• number of secondary follicles is reduced at 12 months of age as compared to controls





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory