All Phenotypes Mlh1<tm1b(EUCOMM)Hmgu> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mlh1^{tm1b(EUCOMM)Hmgu}
targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
MGI:5692538

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mlh1^{tm1b(EUCOMM)Hmgu}/Mlh1^{tm1b(EUCOMM)Hmgu}	C57BL/6N-Mlh1^{tm1b(EUCOMM)Hmgu}/H	MGI:5757364

Allelic Composition	Mlh1^{tm1b(EUCOMM)Hmgu}/Mlh1^{tm1b(EUCOMM)Hmgu}
Genetic Background	C57BL/6N-Mlh1^{tm1b(EUCOMM)Hmgu}/H
Cell Lines	HEPD0522_4_D07

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mlh1^{tm1b(EUCOMM)Hmgu} mutation (0 available); any Mlh1 mutation (44 available)

Data Sources

IMPC Data for Mlh1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

small testis ( J:211773 )

IMPC - HAR

growth/size/body

increased spleen weight ( J:211773 )

IMPC - HAR

hematopoietic system

increased spleen weight ( J:211773 )

IMPC - HAR

homeostasis/metabolism

increased circulating alanine transaminase level ( J:211773 )

IMPC - HAR

increased circulating aspartate transaminase level ( J:211773 )

IMPC - HAR

immune system

increased spleen weight ( J:211773 )

IMPC - HAR

reproductive system

small testis ( J:211773 )

IMPC - HAR

male infertility ( J:211773 )

IMPC - HAR

vision/eye

cataract ( J:211773 )

IMPC - HAR

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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