Phenotypes associated with this allele

• Allele Symbol: Fzd3^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5692578
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fzd3^tm1b(EUCOMM)Hmgu/Fzd3^tm1b(EUCOMM)Hmgu	C57BL/6N-Fzd3^tm1b(EUCOMM)Hmgu/H	MGI:5757148
ht2	Fzd3^tm1b(EUCOMM)Hmgu/Fzd3^+	C57BL/6N-Fzd3^tm1b(EUCOMM)Hmgu/H	MGI:5757147

Genotype
MGI:5757148

hm1

• Allelic Composition: Fzd3^{tm1b(EUCOMM)Hmgu}/Fzd3^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Fzd3^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0675_6_G04

Data Sources

IMPC Data for Fzd3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:5757147

ht2

• Allelic Composition: Fzd3^{tm1b(EUCOMM)Hmgu}/Fzd3⁺
• Genetic Background: C57BL/6N-Fzd3^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0675_6_G04

Data Sources

IMPC Data for Fzd3

adipose tissue

increased total body fat amount ( J:211773 )

♂

IMPC - HAR

behavior/neurological

decreased grip strength ( J:211773 )

♀

IMPC - HAR

homeostasis/metabolism

impaired glucose tolerance ( J:211773 )

♂

IMPC - HAR

skeleton

decreased bone mineral content ( J:211773 )

♂

IMPC - HAR