Phenotypes associated with this allele

• Allele Symbol: Psmc2^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5692582
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Psmc2^tm1b(EUCOMM)Hmgu/Psmc2^tm1b(EUCOMM)Hmgu	C57BL/6N-Psmc2^tm1b(EUCOMM)Hmgu/Ieg	MGI:6263271
ht2	Psmc2^tm1b(EUCOMM)Hmgu/Psmc2^+	C57BL/6N-Psmc2^tm1b(EUCOMM)Hmgu/Ieg	MGI:6263270

Genotype
MGI:6263271

hm1

• Allelic Composition: Psmc2^{tm1b(EUCOMM)Hmgu}/Psmc2^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Psmc2^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0680_4_G08

Data Sources

IMPC Data for Psmc2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:6263270

ht2

• Allelic Composition: Psmc2^{tm1b(EUCOMM)Hmgu}/Psmc2⁺
• Genetic Background: C57BL/6N-Psmc2^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0680_4_G08

Data Sources

IMPC Data for Psmc2

behavior/neurological

abnormal gait ( J:211773 )

IMPC - HMGU

homeostasis/metabolism

increased circulating bilirubin level ( J:211773 )

♂

IMPC - HMGU

decreased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - HMGU

decreased circulating total protein level ( J:211773 )

IMPC - HMGU