Phenotypes associated with this allele

• Allele Symbol: Axin2^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5692597
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Axin2^tm1b(KOMP)Wtsi/Axin2^tm1b(KOMP)Wtsi	C57BL/6N-Axin2^tm1b(KOMP)Wtsi/Bay	MGI:5812992
ht2	Axin2^tm1b(KOMP)Wtsi/Axin2^+	C57BL/6N-Axin2^tm1b(KOMP)Wtsi/Bay	MGI:6261942

Genotype
MGI:5812992

hm1

• Allelic Composition: Axin2^{tm1b(KOMP)Wtsi}/Axin2^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Axin2^{tm1b(KOMP)Wtsi}/Bay
• Cell Lines: EPD0685_5_F12

Data Sources

IMPC Data for Axin2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

craniofacial

abnormal facial morphology ( J:211773 )

IMPC - BCM

protruding tongue ( J:211773 )

♀

IMPC - BCM

abnormal head shape ( J:211773 )

IMPC - BCM

digestive/alimentary system

protruding tongue ( J:211773 )

♀

IMPC - BCM

embryo

abnormal embryo development ( J:211773 )

♂

IMPC - BCM

abnormal embryo size ( J:211773 )

IMPC - BCM

growth/size/body

abnormal facial morphology ( J:211773 )

IMPC - BCM

protruding tongue ( J:211773 )

♀

IMPC - BCM

abnormal head shape ( J:211773 )

IMPC - BCM

abnormal embryo size ( J:211773 )

IMPC - BCM

abnormal body wall morphology ( J:211773 )

IMPC - BCM

limbs/digits/tail

abnormal limb morphology ( J:211773 )

IMPC - BCM

polydactyly ( J:211773 )

IMPC - BCM

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - BCM

vision/eye

abnormal eyelid fusion ( J:211773 )

♀

IMPC - BCM

microphthalmia ( J:211773 )

IMPC - BCM

anophthalmia ( J:211773 )

IMPC - BCM

Genotype
MGI:6261942

ht2

• Allelic Composition: Axin2^{tm1b(KOMP)Wtsi}/Axin2⁺
• Genetic Background: C57BL/6N-Axin2^{tm1b(KOMP)Wtsi}/Bay
• Cell Lines: EPD0685_5_F12

Data Sources

IMPC Data for Axin2

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

integument

abnormal skin coloration ( J:211773 )

IMPC - BCM