Phenotypes associated with this allele

• Allele Symbol: Ncoa3^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5692598
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ncoa3^tm1b(EUCOMM)Wtsi/Ncoa3^tm1b(EUCOMM)Wtsi	C57BL/6N-Ncoa3^tm1b(EUCOMM)Wtsi/H	MGI:5767737
ht2	Ncoa3^tm1b(EUCOMM)Wtsi/Ncoa3^+	C57BL/6N-Ncoa3^tm1b(EUCOMM)Wtsi/H	MGI:5797671

Genotype
MGI:5767737

hm1

• Allelic Composition: Ncoa3^{tm1b(EUCOMM)Wtsi}/Ncoa3^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Ncoa3^{tm1b(EUCOMM)Wtsi}/H
• Cell Lines: EPD0785_2_E05

Data Sources

IMPC Data for Ncoa3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal tooth morphology ( J:211773 )

♂

IMPC - HAR

growth/size/body

abnormal tooth morphology ( J:211773 )

♂

IMPC - HAR

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HAR

skeleton

abnormal tooth morphology ( J:211773 )

♂

IMPC - HAR

vision/eye

persistence of hyaloid vascular system ( J:211773 )

♂

IMPC - HAR

Genotype
MGI:5797671

ht2

• Allelic Composition: Ncoa3^{tm1b(EUCOMM)Wtsi}/Ncoa3⁺
• Genetic Background: C57BL/6N-Ncoa3^{tm1b(EUCOMM)Wtsi}/H
• Cell Lines: EPD0785_2_E05

Data Sources

IMPC Data for Ncoa3

craniofacial

abnormal tooth morphology ( J:211773 )

♂

IMPC - HAR

growth/size/body

abnormal tooth morphology ( J:211773 )

♂

IMPC - HAR

hematopoietic system

increased mean corpuscular hemoglobin ( J:211773 )

♀

IMPC - HAR

thrombocytopenia ( J:211773 )

♂

IMPC - HAR

homeostasis/metabolism

increased circulating bilirubin level ( J:211773 )

♂

IMPC - HAR

impaired glucose tolerance ( J:211773 )

♂

IMPC - HAR

skeleton

abnormal tooth morphology ( J:211773 )

♂

IMPC - HAR

vision/eye

persistence of hyaloid vascular system ( J:211773 )

♂

IMPC - HAR