Phenotypes associated with this allele

• Allele Symbol: Dlg5^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5692705
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dlg5^tm1b(EUCOMM)Wtsi/Dlg5^tm1b(EUCOMM)Wtsi	C57BL/6N-Dlg5^tm1b(EUCOMM)Wtsi/Ucd	MGI:5767634
ht2	Dlg5^tm1b(EUCOMM)Wtsi/Dlg5^+	C57BL/6N-Dlg5^tm1b(EUCOMM)Wtsi/Ucd	MGI:5797480

Genotype
MGI:5767634

hm1

• Allelic Composition: Dlg5^{tm1b(EUCOMM)Wtsi}/Dlg5^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Dlg5^{tm1b(EUCOMM)Wtsi}/Ucd
• Cell Lines: EPD0820_3_A07

Data Sources

IMPC Data for Dlg5

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

hemorrhage ( J:211773 )

IMPC - UCD

embryo

spina bifida ( J:211773 )

IMPC - UCD

growth/size/body

microcephaly ( J:211773 )

IMPC - UCD

limbs/digits/tail

polydactyly ( J:211773 )

IMPC - UCD

syndactyly ( J:211773 )

IMPC - UCD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

nervous system

spina bifida ( J:211773 )

IMPC - UCD

vision/eye

microphthalmia ( J:211773 )

IMPC - UCD

anophthalmia ( J:211773 )

IMPC - UCD

Genotype
MGI:5797480

ht2

• Allelic Composition: Dlg5^{tm1b(EUCOMM)Wtsi}/Dlg5⁺
• Genetic Background: C57BL/6N-Dlg5^{tm1b(EUCOMM)Wtsi}/Ucd
• Cell Lines: EPD0820_3_A07

Data Sources

IMPC Data for Dlg5

cardiovascular system

hemorrhage ( J:211773 )

IMPC - UCD

embryo

spina bifida ( J:211773 )

IMPC - UCD

growth/size/body

microcephaly ( J:211773 )

IMPC - UCD

limbs/digits/tail

polydactyly ( J:211773 )

IMPC - UCD

syndactyly ( J:211773 )

IMPC - UCD

nervous system

spina bifida ( J:211773 )

IMPC - UCD

abnormal brain morphology ( J:211773 )

♂

IMPC - UCD

hydrocephaly ( J:211773 )

♂

IMPC - UCD

vision/eye

microphthalmia ( J:211773 )

IMPC - UCD

anophthalmia ( J:211773 )

IMPC - UCD