All Phenotypes Ift43<tm1b(EUCOMM)Hmgu> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ift43^{tm1b(EUCOMM)Hmgu}
targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
MGI:5692739

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ift43^{tm1b(EUCOMM)Hmgu}/Ift43^{tm1b(EUCOMM)Hmgu}	C57BL/6N-Ift43^{tm1b(EUCOMM)Hmgu}/Bay	MGI:6262675
ht2	Ift43^{tm1b(EUCOMM)Hmgu}/Ift43⁺	C57BL/6N-Ift43^{tm1b(EUCOMM)Hmgu}/Bay	MGI:6288519

Allelic Composition	Ift43^{tm1b(EUCOMM)Hmgu}/Ift43^{tm1b(EUCOMM)Hmgu}
Genetic Background	C57BL/6N-Ift43^{tm1b(EUCOMM)Hmgu}/Bay
Cell Lines	HEPD0821_3_B10

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ift43^{tm1b(EUCOMM)Hmgu} mutation (0 available); any Ift43 mutation (17 available)

Data Sources

IMPC Data for Ift43

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

abnormal heart morphology ( J:211773 )

IMPC - BCM

abnormal heart looping ( J:211773 )

IMPC - BCM

craniofacial

abnormal pharyngeal arch morphology ( J:211773 )

IMPC - BCM

embryo

abnormal pharyngeal arch morphology ( J:211773 )

IMPC - BCM

abnormal embryo turning ( J:211773 )

IMPC - BCM

abnormal neural tube morphology ( J:211773 )

IMPC - BCM

abnormal neural tube closure ( J:211773 )

IMPC - BCM

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - BCM

preweaning lethality, complete penetrance ( J:211773 )

IMPC - BCM

nervous system

abnormal neural tube morphology ( J:211773 )

IMPC - BCM

abnormal neural tube closure ( J:211773 )

IMPC - BCM

abnormal forebrain development ( J:211773 )

IMPC - BCM

abnormal hindbrain development ( J:211773 )

IMPC - BCM

abnormal midbrain development ( J:211773 )

IMPC - BCM

Allelic Composition	Ift43^{tm1b(EUCOMM)Hmgu}/Ift43⁺
Genetic Background	C57BL/6N-Ift43^{tm1b(EUCOMM)Hmgu}/Bay
Cell Lines	HEPD0821_3_B10

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ift43^{tm1b(EUCOMM)Hmgu} mutation (0 available); any Ift43 mutation (17 available)

Data Sources

IMPC Data for Ift43

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

increased circulating creatinine level ( J:211773 )

IMPC - BCM

increased circulating bilirubin level ( J:211773 )

IMPC - BCM

increased circulating cholesterol level ( J:211773 )

IMPC - BCM

increased circulating serum albumin level ( J:211773 )

IMPC - BCM

increased circulating total protein level ( J:211773 )

IMPC - BCM

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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